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Unique to Gram-positive bacteria, wall teichoic acids are anionic glycopolymers cross-stitched to a thick layer of peptidoglycan. The polyol phosphate subunits of these glycopolymers are decorated with GlcNAc sugars that are involved in phage binding, genetic exchange, host antibody response, resistance, and virulence. The search for the enzymes responsible for GlcNAcylation in Staphylococcus aureus has recently identified TarM and TarS with respective αand β-(1-4) glycosyltransferasedoi:10.1073/pnas.1418084112 pmid:25624472 pmcid:PMC4330757 fatcat:ylkx4cvz2vccdhvm4owvkrc6nq