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Transcriptome-wide profiling of multiple RNA modifications simultaneously at single-base resolution
2019
Proceedings of the National Academy of Sciences of the United States of America
The breadth and importance of RNA modifications are growing rapidly as modified ribonucleotides can impact the sequence, structure, function, stability, and fate of RNAs and their interactions with other molecules. Therefore, knowing cellular RNA modifications at single-base resolution could provide important information regarding cell status and fate. A current major limitation is the lack of methods that allow the reproducible profiling of multiple modifications simultaneously,
doi:10.1073/pnas.1817334116
pmid:30872485
pmcid:PMC6452723
fatcat:6n5yddkwdfhmvocg2w5inzwala