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Evolutionary changes in cis-regulatory elements are thought to play a key role in morphological and physiological diversity across animals. Many conserved noncoding elements (CNEs) function as cis-regulatory elements, controlling gene expression levels in different biological contexts. However, determining specific associations between CNEs and related phenotypes is a challenging task. Here, we present a computational "reverse genomics" approach that predicts the phenotypic functions of humandoi:10.1093/molbev/msw001 pmid:26744417 pmcid:PMC4909134 fatcat:l7uibitzf5hmpcn3uw7mvz3iku