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Protein-Mediated Transformation of Lipid Vesicles into Tubular Networks
2013
Biophysical Journal
Key cellular processes are frequently accompanied by protein-facilitated shape changes in the plasma membrane. N-BAR-domain protein modules generate curvature by means of complex interactions with the membrane surface. The way they assemble and the mechanism by which they operate are largely dependent on their binding density. Although the mechanism at lower densities has recently begun to emerge, how membrane scaffolds form at high densities remains unclear. By combining electron microscopy
doi:10.1016/j.bpj.2013.06.039
pmid:23931319
pmcid:PMC3736692
fatcat:edhvqbez35gbzjzku4lhf4wz6e