The Effect of Anti-glaucoma Eyedrops and 0.1% Fluorometholone on Myopic Regression after LASIK or LASEK

Ik Hee Ryu, Hee Sun Kim, Hee Kyung Lee, Jung Sub Kim, Jin Kuk Kim, Wook Kyum Kim
2017 Journal of the Korean Ophthalmological Society  
Purpose: To evaluate the effect of combined medical treatment with anti-glaucoma eyedrops and 0.1% fluorometholone on visual acuity and refractive errors in patients complaining of blurred vision due to myopic regression after laser-assisted in-situ keratomileusis (LASIK) or laser-assisted sub-epithelial keratectomy (LASEK). Methods: This study comprised 155 patients (155 eyes) who were diagnosed with myopic regression after LASIK or LASEK and . The visual acuity and refractive errors were
more » ... ve errors were compared before and after medical treatment and evaluated to determine whether the results differ between LASIK and LASEK. Results: The mean time of medical treatment was 64.1 ± 36.8 months after surgery. The responder group whose vision was improved and whose myopic error was decreased after medical treatment was comprised of 63 patients (41%). Their visual acuity in this group improved -0.21 ± 0.11 logMAR, and the amount of myopic error decreased 0.56 ± 0.32 diopters. The full responder group was 24 patients (15%), and the partial responder group was 39 patients (26%). The frequency of response to medical treatment was higher after LASIK than after LASEK, but the difference was not statistically significant. Conclusions: The combined medical treatment with anti-glaucoma eyedrops and 0.1% fluorometholone was effective in 41% of patients with regard to visual acuity improvement when used for post-LASIK or post-LASEK myopic regression. The medical treatment was effective after both LASIK and LASEK. (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. 라식 라섹의 안정성 및 유효성은 이미 여러 연구 1,2 를 통 하여 입증되었다. 레이저 장비의 발전과 노모그램의 정확도 향상에도 불구하고 라식 후 근시퇴행을 보이는 경우가 5% 에서 28%까지 보고되고 있으며 3-8 수술 후 6개월경에 가장 빈도가 높고, 1-2년 후에도 발생하는 것으로 보고되었다. 대 부분의 연구 4,9-11 에서는 시기와 상관없이 술 후 -0.25디옵터 이상의 근시변화를 근시퇴행으로 정의하였다. 각막굴절 수술 후 발생하는 근시퇴행의 원인은 각막의 전방이동, 각막실질두께의 증가, 각막상피의 변화 등으로
doi:10.3341/jkos.2017.58.1.13 fatcat:c6hl3k6u4zaqllsbi2myt5jkta