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This study aimed to evaluate the effect of Spirulina platensis and moderate exercise on oxidative stress and lipid profiles in the rats. Forty male Wistar rats were allocated to the following 10-week treatments, three times a week: exercise (E, 30 min swimming), S. platensis (SP, 26 mg/Kg); exercise and Spirulina (ES); and control (C). Outcomes were Thiobarbituric Acid Reactive Substances (TBARS) in serum and brain, and cholesterol and triglycerides (TG) in serum. Rats treated with exercisedoi:10.1590/s1516-89132015060216 fatcat:u7b3h3hfjrhprcfsyptfvu3ww4