In vitro differentiation of mouse embryonic stem cells into cardiac cells

Pall Emőke, Lichner Zsuzsanna, Gocza Elen, Groza, Cenariu, Olga Soritau, Tomuleasa
2011 Romanian Biotechnological Letters   unpublished
In its evolution, medicine has imposed a batch of experimental systems that have tried to explain the miracle through which a fertilized cell transformed in blastocyst lies at the basis of all the specialized tissues that form an organism. It seems that the answers derived from these studies intensified the number of medical questions, engendering a new research theme: the embryonic stem cells. Embryonic stem cells are derived from preimplantation blastocyst, they are pluripotent cells and they
more » ... tent cells and they are able to differentiate to different cell lines. This review aims to structure different differentiation protocols most commonly used by different specialists in the field, specifying the role of inducer substances and of the specific methods and substrates used.