Corresponding author, John Tapsall, Department of Microbiology, The Prince of Wales Hospital

Margaret Curran, Charles Watson, Margaret Burgess, Scott Cameron, Jeffrey Hanna, John Kaldor, Margery Kennett, Cathy Mead, Christine Roberts, Ross Andrews, Scott Crerar, Kim Moser (+4 others)
1997 Comm Dis Intell   unpublished
The Australian Meningococcal Surveillance Programme has undertaken meningococcal isolate surveillance by means of a collaborative laboratory-based initiative since 1994. Serogroup data have been enhanced by the addition of serotype and serosubtype information in 1996. Ninety-two per cent of the 297 invasive isolates of Neisseria meningitidis examined in 1996 were serogroup B or C. Serogroup B strains predominated in all States and Territories and were isolated from sporadic cases of
more » ... ases of meningococcal disease. Serogroup C isolates were prominent in New South Wales, Queensland and the Northern Territory, and were also associated with mainly sporadic cases of meningococcal disease. A number of case clusters also occurred in association with serogroup C strains. Although most sporadic cases of meningococcal disease showed a diversity of phenotypes, clusters of cases were noted with the phenotypes C:2a:P1.5 and C:2a:P1.2,5. The number of isolates with the phenotype B:4:P1.4 also increased in New South Wales and Queensland. The proportion of isolates showing decreased susceptibility to the penicillin group of antibiotics (minimal inhibitory concentration, MIC, 0.06 to 0.5 mg/L) increased to 74% in 1996. Three isolates showed reduced susceptibility to rifampicin.