Effects of core iron oxide nanoparticles on microbial control and bacteriostatic activity against Escherichia coli, Staphylococcus aureus and Mycobacterium smegmatis

Rishikesh Kumar, Dept. of Biomedical Informatics Centre, Rajendra Memorial Research Institute Medical Science, Patna 800007, India, Ganesh Chandra Sahoo, VNR Das, Krishna Pandey, Pradeep Das, Dept. of Biomedical Informatics Centre, Rajendra Memorial Research Institute Medical Science, Patna 800007, India, Clinical Medicine, Rajendra Memorial Research Institute Medical Science, Patna 800007, India, Clinical Medicine, Rajendra Memorial Research Institute Medical Science, Patna 800007, India, Dept. of Biomedical Informatics Centre, Rajendra Memorial Research Institute Medical Science, Patna 800007, India
2014 Journal of Scientific and Innovative Research  
The anti-bacterial activity of the Fe3/citric acid/cephalosporin nanoparticles (core) on Staphylococcus aureus (MTCC737), Mycobacterium smegmatis (MTCC994) and Escherichia coli (MTCC443) was tested using this system as an active compound carrier. We have describe the simple method to obtain iron nanoparticles with uniform size distribution by utilizing citric acid and as surface-capping agents the dimensions of Fe nanoparticles were in the 5-20 nm range and they were characterized by High
more » ... tion Transmission Electron Microscopy (HRTEM).The particle size was tailored by tuning the concentration ratio of iron ions to carboxylic acid groups. Fe nanoparticles assisted by citric acid to analyze the interaction different type of cephalosporin against the these bacteria The antibacterial activity was observed in both, citric acid core nanoparticles/cephalosporin and core nanoparticles alone against these pathogen.
doi:10.31254/jsir.2014.3505 fatcat:345i3umjmval7kablqvdfe2ply