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Identifying All Moiety Conservation Laws in Genome-Scale Metabolic Networks
2014
PLoS ONE
The stoichiometry of a metabolic network gives rise to a set of conservation laws for the aggregate level of specific pools of metabolites, which, on one hand, pose dynamical constraints that cross-link the variations of metabolite concentrations and, on the other, provide key insight into a cell's metabolic production capabilities. When the conserved quantity identifies with a chemical moiety, extracting all such conservation laws from the stoichiometry amounts to finding all non-negative
doi:10.1371/journal.pone.0100750
pmid:24988199
pmcid:PMC4079565
fatcat:bqjmqnhbnff5lniq7uswekbbsy