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Hydrogel-Based Drug Delivery Nanosystems for the Treatment of Brain Tumors
2018
Gels
Chemotherapy is commonly associated with limited effectiveness and unwanted side effects in normal cells and tissues, due to the lack of specificity of therapeutic agents to cancer cells when systemically administered. In brain tumors, the existence of both physiological barriers that protect tumor cells and complex resistance mechanisms to anticancer drugs are additional obstacles that hamper a successful course of chemotherapy, thus resulting in high treatment failure rates. Several potential
doi:10.3390/gels4030062
pmid:30674838
pmcid:PMC6209281
fatcat:56uv4qzthbh6boypttzf6r3i64