Solvent-Free Microwave Synthesis of Aryloxypropanolamines by Ring Opening of Aryloxy Epoxides

Rukhsana I. Kureshy, Irshad Ahmad, Kavita Pathak, N. H. Khan, Sayed H. R. Abdi, H. C. Bajaj, Eringathodi Suresh
2009 Research Letters in Organic Chemistry  
The ring opening reaction of aryloxyepoxides with isopropylamine under solvent-free microwave irradiation produced therapeutically useful -blockers-aryloxypropanolamines in excellent yield (up to 98%) in 10 minutes which is considerably less than the time taken in classical heating ( hours).
doi:10.1155/2009/109717 fatcat:5erbnejoxnaydjf6yp3rk6jobu