Modelling the thermal inactivation of viruses from the Coronaviridae family in suspensions or on surfaces with various relative humidities [article]

Laurent Guillier, Sandra Martin-Latil, Estelle Chaix, Anne Thebault, Nicole Pavio, Sophie Le Poder, Christophe Batejat, Fabrice Biot, Lionel Koch, Don Schaffner, Moez Sanaa
2020 medRxiv   pre-print
Temperature and relative humidity are major factors determining virus inactivation in the environment. This article reviews inactivation data of coronaviruses on surfaces and in liquids from published studies and develops secondary models to predict coronaviruses inactivation as a function of temperature and relative humidity. A total of 102 D-values (time to obtain a log10 reduction of virus infectivity), including values for SARS-CoV-2, were collected from 26 published studies. The values
more » ... ined from the different coronaviruses and studies were found to be generally consistent. Five different models were fitted to the global dataset of D-values. The most appropriate model considered temperature and relative humidity. A spreadsheet predicting the inactivation of coronaviruses and the associated uncertainty is presented and can be used to predict virus inactivation for untested temperatures, time points or new coronavirus strains.
doi:10.1101/2020.05.26.20114025 fatcat:3xmk7ituzbajjelanpqhjxzjk4