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Nutritional and Endocrine-Metabolic Aberrations in Women with Functional Hypothalamic Amenorrhea1
Journal of Clinical Endocrinology and Metabolism
The development of functional hypothalamic amenorrhea (FHA) in weight-stable, nonathletic women has long been thought to be psychogenic in origin. This study was designed to gain insight into the possibility that nutritional deficits and compensatory endocrine-metabolic adaptations contribute to the development and maintenance of FHA of the psychogenic type. Nutritional intake, insulin sensitivity, and 24-h dynamics of insulin/glucose, cortisol, leptin, somatotropic, and LH axes weredoi:10.1210/jcem.83.1.4502 pmid:9435412 fatcat:oenlmxwrbnfqle22rber32lcki