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Neuronal and Cardiovascular Potassium Channels as Therapeutic Drug Targets
2015
Journal of Biomolecular Screening
Potassium (K + ) channels, with their diversity, often tissue-defined distribution, and critical role in controlling cellular excitability, have long held promise of being important drug targets for the treatment of dysrhythmias in the heart and abnormal neuronal activity within the brain. With the exception of drugs that target one particular class, ATP-sensitive K + (K ATP ) channels, very few selective K + channel activators or inhibitors are currently licensed for clinical use in
doi:10.1177/1087057115601677
pmid:26303307
pmcid:PMC4576507
fatcat:5i6cevbzo5axxilvnggwxqmi4q