Level of ART Adherence and Associated Factors among HIV Sero- Positive Adult on Highly Active Antiretroviral Therapy in Debre Markos Referral Hospital, Northwest Ethiopia

Mulugeta Asmare Mekonnen Aychiluhem
2014 Journal of Antivirals & Antiretrovirals  
The current number of sero-positive HIV patients in Ethiopia is about 700,000 with overall estimated prevalence of 1.5%. The introduction of combination ART including protease inhibitors has resulted in striking reductions in HIV-related mortality. Numerous reports have documented that the key to the success of the new HAART is the ability and willingness of HIV-positive individuals to adhere to complex ART regimens, and at least 95% adherence is required for ART regimens to be fully effective.
more » ... be fully effective. Objectives: The main aim of this study was to assess level of adherence to ART and associated factors among HIV sero-positive adult on HAART. Methods: An institutional based cross-sectional study was conducted on 377 participants selected by systematic sampling technique. A pre-tasted structured questionnaire was used by employing interview to collect necessary data. The collected data were analyzed using SPSS 16.0 version. Significance level was set at 95% CI and p-value of <0.05. Results: The adherence rate of the study participants was 88.6%. Monthly family income [(AOR 0.3, 95%CI 0.13, 0.69)], delayed in taking ART drugs AIDS [(AOR 0.6, 95% CI 0.16,0.88)], fitness of daily treatment schedule [(AOR 9.7, 95% CI 4.6,28)] and consistently taking of ART drugs [(AOR 5.7,95%CI, 2.6,25.3)] were significantly associated with ART adherence.
doi:10.4172/jaa.10000107 fatcat:zsnd2zssajfydlmj4ea2y6wsxu