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In vitro effects of arylimidamides against Besnoitia besnoiti infection in Vero cells
The in vitro effects of 4 arylimidamides (DB811, DB786, DB750 and DB766) against the proliferative tachyzoite stage of the apicomplexan parasite Besnoitia besnoiti were investigated. These four compounds had been shown earlier to exhibit in vitro activities in the nanomolar range against the related apicomplexans Neospora caninum and Toxoplasma gondii. Real-time-PCR was used to assess B. besnoiti intracellular proliferation in vitro. Preliminary assessment by light microscopy identified DB811doi:10.1017/s0031182011000114 pmid:21349220 fatcat:qg6vhhzhlnejvjwh7wwgrmqkci