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Targeted recovery of novel phylogenetic diversity from next-generation sequence data
2012
The ISME Journal
Next-generation sequencing technologies have led to recognition of a so-called 'rare biosphere'. These microbial operational taxonomic units (OTUs) are defined by low relative abundance and may be specifically adapted to maintaining low population sizes. We hypothesized that mining of lowabundance next-generation 16S ribosomal RNA (rRNA) gene data would lead to the discovery of novel phylogenetic diversity, reflecting microorganisms not yet discovered by previous sampling efforts. Here, we test
doi:10.1038/ismej.2012.50
pmid:22791239
pmcid:PMC3475379
fatcat:i335wzhigbaetaxzmnh75y6umq