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Krüppel-like factor 10 (KLF10) is transactivated by the transcription factor C/EBPβ and involved in early 3T3-L1 preadipocyte differentiation
Journal of Biological Chemistry
Edited by Jeffrey E. Pessin Adipose tissue stores energy and plays an important role in energy homeostasis. CCAAT/enhancer-binding protein ␤ (C/EBP␤) is an important early transcription factor for 3T3-L1 preadipocyte differentiation, facilitating mitotic clonal expansion (MCE) and transactivating C/EBP␣ and peroxisome proliferator-activated receptor-␥ (PPAR␥) to promote adipogenesis. C/EBP␤ is induced early, but the expression of antimitotic C/EBP␣ and PPAR␥ is not induced until ϳ48 h. Thedoi:10.1074/jbc.ra118.004401 pmid:30026232 fatcat:o7mdfpo64vg35davrkbiaehd6a