SYNTHESIS AND CHARATERIZATION OF COPPER NANOPARTICLES AND EVALUATION OF ANTIBACTERIAL ACTIVITY

N. Karikalan
2018 RASAYAN Journal of Chemistry  
The nanotechnology has been developed in recent years due to the wide application in the human beings. One of the famous nanomaterials is copper nanoparticles. The copper nanoparticles have been reported to have strong antibacterial activity. Nowadays there are many environmental problems and illness caused by the microbial pathogen. It is widely agreed that nanoparticles are clusters of atoms in the size range of 1-100 nanometer. The present study included the chemical reduction of copper
more » ... tion of copper chloride through trisodium citrate and testing for their antimicrobial activity. The aqueous copper chloride exposed to the trisodium citrate results in the synthesis of copper nanoparticles. The pH and viscosity of the copper nanoparticles monitored and indicates the stability of the particles. Ultraviolet-visible spectrum and Fourier-transform infrared spectroscopy further confirmed in the synthesized copper nanoparticles. These synthesized copper nanoparticles were further confirmed by using a scanning electron microscope. The scanning electron microscope analysis showed the particle size between 44.50 nanometers as well the spherical structure of the nanoparticles. The proven antibacterial activity of synthesized copper nanoparticles against Escherichia coli established. It is confirmed that copper nanoparticles are capable of rendering high antibacterial efficacy and hence has a great potential in the preparation of drugs used against bacterial diseases. Applications of copper nanoparticles based on these findings may lead to valuable discoveries in various fields such as medical devices and antimicrobial systems.
doi:10.31788/rjc.2018.1143068 fatcat:uwwvwsgafvasdh4dneqqa74veu