Objective. Estimation of expediency for peritonization of the stapler resection line, aiming to prevent the stapler suture hemorrhage and insufficiency. Маterials and methods. The investigation was conducted on laboratory rabbits, to which the sleeve gastric resection was performed: in 9 experimental animals (Group 1) – with peritonization of the stapler suture line, in experimental animals (Group 2) – without peritonization. Structural changes of gastric wall in the stapler suture portion in

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... th groups of experimental animals were investigated. Results. Peritonization of the stapler suture line have caused exaggeration of the gastric walls ischemic changes. Conclusion. Peritonization of the sleeve gastric resection line promotes prophylaxis of postoperative hemorrhage from the stapler suture, but do not prevent its insufficiency.