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Metamodulation of a Spinal Locomotor Network by Nitric Oxide
2004
Journal of Neuroscience
Flexibility in the output of spinal networks can be accomplished by the actions of neuromodulators; however, little is known about how the process of neuromodulation itself may be modulated. Here we investigate the potential "meta"-modulatory hierarchy between nitric oxide (NO) and noradrenaline (NA) in Xenopus laevis tadpoles. NO and NA have similar effects on fictive swimming; both potentiate glycinergic inhibition to slow swimming frequency and GABAergic inhibition to reduce episode
doi:10.1523/jneurosci.1817-04.2004
pmid:15509743
fatcat:mexqks2mvjhurh53yhafecrjfe