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Refinement Recommendations for Intravenous Injection and Body Heat Conservation in Mongolian Gerbils used in SPECT Studies

Christel Palmyre Henri Moons, Kathelijne Peremans, Philippe Büscher, Simon Vermeire, Eva Vandermeulen, Kurt Audenaert, Katleen Hermans, Frank Olof Ödberg
2014

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This paper describes two aspects of Single Photon Emission Computed Tomography (SPECT) which have been refined for use in small animals, as demonstrated by a study on Mongolian gerbils: intravenous injection of radiotracers in the femoral vein and body heat conservation in animals anaesthetized at the time of scanning. Elaborating on recommendations made by other authors, we have combined chemical and physical restraint to optimize injection efficiency as well as to reduce handling time of the
more » ... nimals. Finally, we provide a detailed description of a SPECT-compatible waterheated scanning bed, the application of which we believe is not limited to scintigraphic studies.
doi:10.23675/sjlas.v35i4.155 fatcat:akt75k73hrgprbdzhio7f3ljsq
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Christel Palmyre Henri Moons, Kathelijne Peremans, Philippe Büscher, Simon Vermeire, Eva Vandermeulen, Kurt Audenaert, Katleen Hermans, Frank Olof Ödberg. "Refinement Recommendations for Intravenous Injection and Body Heat Conservation in Mongolian Gerbils used in SPECT Studies." (2014) No 4 (2008)