Halka Boyunlu Sülün'de (Phasianus colchicus) Termostabil Newcastle Hastalığı Aşı Suşu I-2'ye Karşı Humoral İmmun Yanıtın Gelişimi
Development of Humoral Immune Response to Thermostable Newcastle Disease Vaccine Strain I-2 in Ring-Necked Pheasant (Phasianus colchicus)

Faisal SIDDIQUE, Rao ZAHID ABBAS, Asif IQBAL, Masood RABBANI, Azhar RAFIQUE, Irshad HUSSAIN, Rais AHMED, M. Shahid MAHMOOD, Alireza LOTFI
2021 Kafkas Universitesi Veteriner Fakultesi Dergisi  
Newcastle Disease (ND) was ranked as a List A and trade limited disease by the World Health Organization. It is one of the deadly diseases of domestic and zoo birds especially pheasants that are highly susceptible species to Newcastle disease virus (NDV). This study was designed to determine the humoral immune response (HIR) of thermostable NDV vaccine strain I-2 in same age pheasants. For this purpose, forty-five pheasants of the same age were separated and placed in cages. Thermostable NDV
more » ... Thermostable NDV I-2 vaccine was mixed with feed and administered through oral route to the same age pheasants. HIR was detected using haemagglutination inhibition test (HI) and enzyme linked immunosorbent assay (ELISA) on 0, 7 th , 14 th , 21 th and 28 th days post-vaccination (DPV). Optimum geometric mean anti-NDV-ELISA (2380) and anti-NDV-HI (Log27.5) antibodies titers were identified on 14 th DPV. It was concluded that the oral administration of NDV I-2 strain is able to elicit a protective immune response in pheasants. Moreover, the use of this novel vaccine technique at the same age of pheasants overwhelms the attempt to catch these birds for single vaccination.
doi:10.9775/kvfd.2020.25021 fatcat:rb6b2z5iijhjrdyaoqsgrv4nea