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Assessing the accuracy of phylogenetic rooting methods on prokaryotic gene families
2020
PLoS ONE
Almost all standard phylogenetic methods for reconstructing gene trees result in unrooted trees; yet, many of the most useful applications of gene trees require that the gene trees be correctly rooted. As a result, several computational methods have been developed for inferring the root of unrooted gene trees. However, the accuracy of such methods has never been systematically evaluated on prokaryotic gene families, where horizontal gene transfer is often one of the dominant evolutionary events
doi:10.1371/journal.pone.0232950
pmid:32413061
fatcat:o2jga2k45nbfzoygyyxbnsafsa