Simultaneous Registration and Segmentation of Anatomical Structures from Brain MRI [chapter]

Fei Wang, Baba C. Vemuri
2005 Lecture Notes in Computer Science  
In this paper, we present a novel variational formulation of the registration assisted image segmentation problem which leads to solving a coupled set of nonlinear PDEs that are solved using efficient numerical schemes. Our work is a departure from earlier methods in that we have a unified variational principle wherein non-rigid registration and segmentation are simultaneously achieved; unlike previous methods of solution for this problem, our algorithm can accommodate for image pairs having
more » ... y distinct intensity distributions. We present examples of performance of our algorithm on synthetic and real data sets along with quantitative accuracy estimates of the registration.
doi:10.1007/11566465_3 fatcat:lvfhn3tsqbh7xhy2iqxurpwauu