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11C-Methionine-PET: A novel and sensitive tool for monitoring of early response to treatment in multiple myeloma
2015
OncoTarget
Multiple myeloma (MM) remains an essentially incurable hematologic malignancy. However, new treatment modalities and novel drugs have been introduced and thus additional tools for therapy monitoring are increasingly needed. Therefore, we evaluated the radiotracers 11 C-Methionine (paraprotein-biosynthesis) and 18 F-FDG (glucose-utilization) for monitoring response to anti-myeloma-therapy and outcome prediction. Influence of proteasome-inhibition on radiotracer-uptake of different MM cell-lines
doi:10.18632/oncotarget.3053
pmid:25762625
pmcid:PMC4480763
fatcat:qobvmo27hrhpxhq66ywljynvjy