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Proteins are built with molecular modular building blocks such as an a-helix, b-sheet, loop region and other structures. This is an economical way of constructing complex molecules. Periodicity analysis of protein sequences has allowed us to obtain meaningful information concerning their structure, function and evolution. In this work, complex demodulation (CDM) is introduced to detect functional regions in protein sequences data. More specifically, we analyzed bZIP and bHLH-PAS proteindoi:10.1016/j.mbs.2007.01.004 pmid:17374384 fatcat:t5l6sqnttvenvoi73poj5hnnu4