141/150 words) The effects of change of residence on pollinosis symptoms remain unclear. We investigated effects of geographical change of residence on pollinosis symptoms among university freshmen. All freshmen (n=2,142) entering Shinshu University in 2011 completed self-administered questionnaires. Associations between history of pollinosis and environmental factors were assessed. Subjects were classified into three groups according to pollen count at previous residences (stationary, low

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... n and high pollen). Pollinosis both before and after relocation were compared among and within the groups. Of the 1,558 subjects, 540 (34.7%) developed pollinosis before, and 483 (31.0%) after entering university. The rates of pre-and post-university entrance pollinosis were 40.0% and 32.5% in the high pollen group (P<0.001) but were similar in the other two groups. Pollinosis symptoms decreased among students that moved from high to low pollen areas, indicating that pollinosis was affected by geographic environmental factors.