Eosinophil recruitment in TNF-receptor-deficient mice

Malcolm Shepherd
2001 Respiratory Research  
Context Tumour necrosis factor (TNF) is increased in the airways of asthmatic patients; however, its contribution to allergic inflammation is unclear. Two different receptors (p55 and p75) in the mouse mediate different inflammatory responses to TNF-a. In this study TNF receptor gene knockout mice were used to investigate the role of TNF in allergic inflammation.
doi:10.1186/rr-2001-68501 fatcat:c4osac7svfazhpcplpj53pb7f4