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Glial activation in nitrous oxide toxicity is related to oxidative stress and glutamate excitotoxicity
2017
Canadian Journal of Biotechnology
Myelin disorders can be due to diverse mechanisms such as autoimmune, parainfectious, metabolic or toxic. The prototype of immune mediated demyelination is multiple sclerosis. To understand the underlying mechanism of cell damage in vitamin b12 deficiency, a number of animal models have been used which include total gastrectomy (TGX), cobalamine deficient diet and N 2 O exposure (Tredici G, et al., 1998; Scalabrino G, 2001). Six adult wistar male rats were exposed to N 2 O oxygen mixture in 1:1
doi:10.24870/cjb.2017-a262
fatcat:tseygypswve6haiabitvh4v46i