A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2019; you can also visit the original URL.
The file type is
cGMP-dependent protein kinase (PKG) mediates the anticontractile capacity of perivascular adipose tissue
Aim The aim of this study was to investigate the role of cGMP-dependent protein kinase (PKG) in mediating the anticontractile function of perivascular adipose tissue (PVAT) and whether its activation can rescue PVAT activity which is lost in an experimental model of inflammation. Methods and results Contractile responses to norepinephrine were assessed using wire myography from small arterial segments obtained from PKG 2/2 , PKG +/+ , adipo 2/2 , and C57Bl6/J mice with and without PVAT duringdoi:10.1093/cvr/cvt229 pmid:24095868 fatcat:zezjl4ine5ewpiixntd5vqya5i