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Molecular Mechanism of Congenital Heart Disease and Pulmonary Hypertension
Despite improvements over the past 30 years, 10-year pediatric heart transplantation survival rates remain low and mechanical support is both expensive and relatively unavailable. In contrast to isolated cell therapies, 354 implantable engineered cardiac tissues (ECTs) recover myocardial mass and function, creating the opportunity for cardiac recovery rather than replacement. Our ECT research has progressed from using embryonic avian and rodent cell compositions to human induced pluripotentdoi:10.1007/978-981-15-1185-1_54 fatcat:xrvtumhacjbohmjs5a4prv5fia