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Experimental immunology Determination of mRNA three Toll-like receptors in human carcinoma cell lines
2012
Central European Journal of Immunology
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Toll-like receptors (TLRs) are now considered to be active players in tumor-host interactions. Tolllike receptor protein expression on/in cancer cell depends apparently on the level of RNA transcription. Based on previous work showing presence of TLR mRNA in six carcinoma cell lines, it was attempted to determine quantitatively mRNA of TLR-2, TLR-3 and TLR-4 by rt PCR. It has been shown that the expression of mRNA of three TLRs tested was uneven among examined cell lines. These data imply that
doi:10.5114/ceji.2012.32718
fatcat:4jm6cunzcfbz7nm3apxvdfnrua