Osseous metaplasia in a kidney allograft

S. Bataille, L. Daniel, T. Legris, H. Vacher-Coponat, R. Purgus, Y. Berland, V. Moal
2010 Nephrology, Dialysis and Transplantation  
Osseous metaplasia is defined by the presence of heterotopic normal bone tissue in a soft tissue. The bone matrix is associated with osteoblasts, osteoclasts, adipocytes and haematopoietic stem cells. Osseous metaplasia pathophysiology is not well known, but many factors have been incriminated including chronic inflammation and chronic ischaemia. We describe the second case of osseous metaplasia in a kidney allograft. Numerous factors might favour its development including factors linked to transplantation failure environment.
doi:10.1093/ndt/gfq490 pmid:20709743 fatcat:kd2vl5cfffenzjjfqn4njuyqzi