Ethnic differences in SERPINA1 allele frequencies may partially explain national differences in COVID-19 fatality rates [article]

Guy Shapira, Noam Shomron, David Gurwitz
2020 medRxiv   pre-print
COVID-19 infection and fatality rates vary considerably between countries. We present preliminary evidence that these variations may in part reflect ethnic differences in the frequencies of polymorphic alleles of SERPINA1, coding for alpha-1 antitrypsin, the major blood serine protease inhibitor.
doi:10.1101/2020.08.24.20179226 fatcat:hnrkzpomsnfxvpt3xbicwyaq2a