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Trends in Gliosis in Obesity, and the Role of Antioxidants as a Therapeutic Alternative
2022
Antioxidants
Obesity remains a global health problem. Chronic low-grade inflammation in this pathology has been related to comorbidities such as cognitive alterations that, in the long term, can lead to neurodegenerative diseases. Neuroinflammation or gliosis in patients with obesity and type 2 diabetes mellitus has been related to the effect of adipokines, high lipid levels and glucose, which increase the production of free radicals. Cerebral gliosis can be a risk factor for developing neurodegenerative
doi:10.3390/antiox11101972
fatcat:6uxnrw6qmjd4be35czyu5fy5e4