GELA: A Software Tool for the Analysis of Gene Expression Data

Emanuel Weitschek, Giulia Fiscon, Giovanni Felici, Paola Bertolazzi
2015 2015 26th International Workshop on Database and Expert Systems Applications (DEXA)  
With the development of Molecular Biology during the last decades, we are witnessing an exponential growth of both the volume and the complexity of biological data. For example, the Human Genome Project provided the sequence of the 3 billion DNA bases that constitute the human genome. And, consequently, we are provided too with the sequences of about 100,000 proteins. Therefore, we are entering the post-genomic era: after having focused so many efforts on the accumulation of data, we have now
more » ... focus as much effort, and even more, on the analysis of these data. Analyzing this huge volume of data is a challenging task because, not only, of its complexity and its multiple and numerous correlated factors, but also, because of the continuous evolution of our understanding of the biological mechanisms. Classical approaches of biological data analysis are no longer efficient and produce only a very limited amount of information, compared to the numerous and complex biological mechanisms under study. From here comes the necessity to use computer tools and develop new in silico high performance approaches to support us in the analysis of biological data and, hence, to help us in our understanding of the correlations that exist between, on one hand, structures and functional patterns of biological sequences and, on the other hand, genetic and biochemical mechanisms. Knowledge Discovery and Data Mining (KDD) are a response to these new trends. Topics of BIOKDD workshop include, but not limited to:
doi:10.1109/dexa.2015.26 dblp:conf/dexaw/WeitschekFFB15 fatcat:qx2mvymjgbaqdowyeioxfdvlti