Serum Levels of Vitamin D, Magnesium, Calcium, Iron, and TIBC in HIV-Infected Patients
Journal of Kermanshah University of Medical Sciences
Vitamin D insufficiency and HIV infection are both risk factors for chronic disorders. Several studies on small groups of male HIV-infected patients have reported alterations of calcium and bone metabolisms. This study aimed to evaluate serum levels of vitamin D, magnesium, calcium, iron, and TIBC in HIV-infected patients compared with controls in the west of Iran. Methods: In a case-control study approved by the Ethics Committee of Kermanshah University of Medical Sciences, 98 prisoners with
... 98 prisoners with HIV and 98 controls were selected in 2016. Age, sex, vitamin D, calcium, magnesium, iron and total iron binding capacity (TIBC) were checked for all participants in both groups. Also, CD4 was checked in all HIV-infected patients. Results: The mean age ± SD (range) of HIV-infected and control groups was 40.11 ± 7.73 (21.68) and 45.59 ± 18.61 (18.85) years, respectively. Vitamin D, calcium, iron, and TIBC levels were significantly different in these two groups (P < 0.05). Vitamin D deficiency was higher in the HIV-infected group than that in the control group. Furthermore, calcium, iron and TIBC levels were higher in the HIV-infected group compared with those in the control group. Conclusions: This study showed that calcium, iron and TIBC levels were significantly higher in HIV-infected patients compared with those in the control group. Moreover, vitamin D insufficiency and deficiency were higher in HIV-infected patients. The patients with CD4 < 200 cells/mm 3 had less calcium and iron levels compared with 200 -500 and > 500 cells/mm 3 .