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Scholars Research Library Der Pharma Chemica
In the present study, we have reported the synthesis of various Imidazo [2, 1-b] [1, 3, 4] thiadiazole derivatives. These derivatives are of interest because they exhibit a wide range of pharmacological activities. In the reactions we have reacted various substituted benzoic acids with thiosemicarbazide in the presence of Phosphorous Oxychloride to yield the substituted 1, 3, 4-thiadiazole nucleus. Further this was treated with various substituted bromoacetyl compounds to synthesize variousfatcat:cok4as22xjc5pptqashqtefzkm