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A Markov chain model of particle deposition in the lung
Particle deposition in the lung during inhalation is of interest to a wide range of biomedical sciences due to the noninvasive therapeutic route to deliver drugs to the lung and other organs via the blood stream. Before reaching the alveoli, particles must transverse the bifurcating network of airways. Computational fluid mechanical studies are often used to estimate high-fidelity flow patterns through the large conducting airways, but there is a need for reduced-dimensional modeling thatdoi:10.1038/s41598-020-70171-2 pmid:32782272 fatcat:bxrvts7p2jf47dleyowburunmu