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In recent years graphical models have become an increasingly important tool for the structural analysis of genome-wide expression profiles at the systems level. Here we present a new graphical modelling technique, which is based on decomposable graphical models, and apply it to a set of gene expression profiles from acute lymphoblastic leukemia (ALL). The new method explains probabilistic dependencies of expression levels in terms of the concerted action of underlying genetic functionaldoi:10.1089/1536231041388375 pmid:15268775 fatcat:5m2q7hf32zbyrpdnnol7ejef6q