P2-323: Outcome of patients with stage III and IV non-small cell lung cancer in Marmara University Hospital, Istanbul, Turkey

Perran F. Yumuk, Mehmet Teomete, Faysal Dane, Devrim Cabuk, Hale B. Caglar, Ufuk Abacioglu, Gul Basaran, Nazim S. Turhal
2007 Journal of Thoracic Oncology  
a total of 46 NSCLC patients were treated. Two patients were not evaluable because we could not find his data file. Characteristics of patients were as follows: Median age 56 years (range 41-72), male 41, female 3 and PS 0 = 7 / 1 = 37. Histologic diagnosis was adenocarcinoma in 17 patients, squamous cell carcinoma in 5 and undifferentiated NSCLC in 22. Brain metastasis were present 7 patients (16%) prior starting the treatment. Median number of cycles were 3.0 (range 1-6). In 45 evaluable
more » ... nts, complete responses were seen in 1 patient ( 2.3%), partial response in 15 (34.1%) and disease stabilization in 19 ( 43.2%). In total of 140 cycles, grade 3-4 neutropenia, grade 3-4 leukopenia and grade 3-4 anemia occured in 16.5%, 10% and 0.7% respectively. One fatal event was observed. The median survival was 285 days (95% CI ) and at 1 and 2 years survival were 39% and 9.5%, respectively. Conclusion: The combination of cisplatin plus vinorelbine is an active and tolerable regimen in Turkish patients with metastatic NSCLC.
doi:10.1097/01.jto.0000284031.87598.62 fatcat:qdtl7x2izvhqpdobawfhxujfse