The paper considers the study of the problem of the development of the scientific potential of the network interaction of economic agents in the digital environment based on the ecosystem methodology. The study of this problem was based on the use of analytical methods for reviewing the scientific interdisciplinary literature of international databases, methods for analyzing the digital transformation of management relations "ecosystem is a management system of an organization", as well as

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... ds for integrating heterogeneous economic data on the development of economic relations in the development of platform ecosystems. The most important result of the research is the conceptual substantiation of the formation of the scientific potential of the network interaction of economic agents based on the ecosystem development of forms of technological entrepreneurship and lifelong learning. The ecosystem methodology proposed by the authors is based on the identification of three types of relations "ecosystem is a management system": intersystematic relations; relations of intra-organizational regulation; platform management relationship. The significance of the results obtained is due to the importance of developing the economy of ecosystems on the basis of interdisciplinary network integrativity of the interaction of economic agents in the digital environment.