Predicting enzyme class from protein structure using Bayesian classification

Luiz C Borro, Stanley R M Oliveira, Michel E B Yamagishi, Adaulto L Mancini, José G Jardine, Ivan Mazoni, Edgard H dos Santos, Roberto H Higa, Paula R Kuser, Goran Neshich
2006 Genetics and Molecular Research  
Predicting enzyme class from protein structure parameters is a challenging problem in protein analysis. We developed a method to predict enzyme class that combines the strengths of statistical and data-mining methods. This method has a strong mathematical foundation and is simple to implement, achieving an accuracy of 45%. A comparison with the methods found in the literature designed to predict enzyme class showed that our method outperforms the existing methods.
pmid:16755510 fatcat:4n7ahzgyynannmiyvceierftcy