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the spread of the infection, while schizogony increases the infection of the host. Coceidia consequently present alternating, sexual and non-sexual generations. Lühe then recounts step by step the development of our present knowledge of the mode of infection of human malaria and the rôle played by certain mos¬ quitoes, especially Anopheles claviger, as one of the hosts necessary for the development of the malarial organism. These things have been described from time to time in these columns.doi:10.1001/jama.1900.02460210052008 fatcat:zbmofjfhtve2faxetmcgilsf6y