SENSITIVITY PATTERN AND FREQUENCY OF METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS IN CHRONIC SUPPURATIVE OTITIS MEDIA
Aim: To describe the incidence of MRSA and its sensitivity to various antibiotics in patients with chronic purulent otitis media. Place and Duration: In the department of ENT, Services Hospital Lahore for one-year duration from January 2019 to January 2020. Material and methods: This descriptive multi-center study was conducted at Departments of ENT. Patients with unilateral or bilateral active chronic suppurative otitis media attending the outpatient clinic were included in the study. Pus
... the study. Pus samples were collected from the discharging ears and sent to the Microbiology Department for culture and sensitivity studies. The smears were obtained using sterile cotton swabs, then incubated and identified. Drug susceptibility was determined by disc-diffusion method. Results: From the clinical specimens of 250 patients enrolled in the study, microbiological culture was yielded from 208(83.2%) specimens. Out of total 250 cultured isolates, MRSA was isolated in 24/250(9.6%) cases. Drug sensitivities pattern showed that vancomycin had highest sensitivity 24/24(100%) while the organism showed complete resistance to augmentin, gentamicin, ceftriaxone. Conclusion: MRSA was 100% sensitive to vancomycin while the organism showed complete resistance to aminoglycosides, penicillins, and cephalosporins. Conclusion: Although MRSA was 100% sensitive to vancomycin, the body was fully resistant to aminoglycosides, penicillin and cephalosporins. Keywords: purulent otitis media, culture and susceptibility, MRSA, vancomycin.