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Synteny-guided resolution of gene trees clarifies the functional impact of whole genome duplications
2020
Molecular biology and evolution
Whole genome duplications (WGD) have major impacts on the evolution of species, as they produce new gene copies contributing substantially to adaptation, isolation, phenotypic robustness, and evolvability. They result in large, complex gene families with recurrent gene losses in descendant species that sequence-based phylogenetic methods fail to reconstruct accurately. As a result, orthologs and paralogs are difficult to identify reliably in WGD-descended species, which hinders the exploration
doi:10.1093/molbev/msaa149
pmid:32556216
fatcat:lfyiprkzdnbsxgouylkgnlxic4