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Bioavailable Estradiol May Be an Important Determinant of Osteoporosis in Men: The MINOS Study
2001
Journal of Clinical Endocrinology and Metabolism
During recent years, experimental data, case reports, and epidemiological studies have suggested an important role for estradiol in bone metabolism in men. In a cohort of 596 men, aged 51-85 yr, we measured bone mineral density (BMD) of the lumbar spine, hip, total body, and forearm; serum levels of sex steroid hormones [total and free testosterone, total estradiol (17E 2 ), bioavailable estradiol (bio-17E 2 ), androstenedione, and sex hormone-binding globulin]; and markers of bone turnover
doi:10.1210/jc.86.1.192
pmid:11232000
fatcat:cgi7ejxoxnhhdlcpztb6ip4gze