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Annals of Neurology
Objective: Relationships between the apolipoprotein E 4 allele and electroencephalographic (EEG) rhythmicity have been demonstrated in Alzheimer's disease (AD) patients but not in the preclinical stage prodromic to it, namely, mild cognitive impairment (MCI). The present multicentric EEG study tested the hypothesis that presence of 4 affects sources of resting EEG rhythms in both MCI and AD subjects. Methods: We enrolled 89 MCI subjects (34.8% with 4) and 103 AD patients (50.4% with 4). Restingdoi:10.1002/ana.20724 pmid:16358334 fatcat:ab42ipw3nzbyjnzdhw6spkmvcy